This document contains software quality assurance (SQA) assessment criteria and guidelines for assessing the safety software currently in use in the safety analysis and design of structures, systems and components (SSCs) in Department of Energy (DOE) defense nuclear facilities. The criteria and guidelines fulfill Commitment 184.108.40.206 of the Implementation Plan (IP) for Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2002-1, Quality Assurance for Safety Software at Department of Energy Defense Nuclear Facilities. Commitment 4.2.4 of the IP specifies three actions DOE will take to assess the processes in place to ensure that the safety software currently used in the analysis and design of defense nuclear facilitie s is adequate. Commitment 220.127.116.11 requires the Office of Environment, Safety and Health (EH) to develop and issue a Criteria Review and Approach Document (CRAD) for the identification, selection, and assessment of that safety software. Commitments 18.104.22.168 and 22.214.171.124 require the Program Secretarial Officers (PSOs) and Field Element Managers to develop a schedule and complete the assessments using this CRAD.